SMBC Nikko and Nethermind Partner with Uniswap Labs, Base, and Nyx to Launch Institutional DeFi Gateway in Japan

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SMBC Nikko and Nethermind Partner with Uniswap Labs, Base, and Nyx to Launch Institutional DeFi Gateway in Japan

Japanese brokerage giant SMBC Nikko Securities and UK-based blockchain infrastructure firm Nethermind have signed a Memorandum of Understanding with Uniswap Labs, Base, and the Nyx Foundation to build a compliant, institutional-grade decentralized finance (DeFi) liquidity framework for the Japanese market.

Dubbed the "DeFi Gateway," the project seeks to bridge traditional finance and on-chain markets. The initiative targets a completion date of mid-2027 and aims to establish user-friendly access to automated market makers (AMMs) and liquidity deployment strategies while meeting strict regulatory standards.

Collaborative Framework and Core Objectives

First conceptualized by SMBC Nikko and Nethermind in March 2026, the initiative has expanded to incorporate global protocols and technical research foundations to build out the necessary infrastructure.

Key components of the initiative include:

  • AI-Driven Infrastructure: Developing agentic vaults and verifiable AI interfaces to automate and simplify on-chain onboarding for Japanese investors.
  • Regulatory-Compliant Frameworks: Utilizing Uniswap V4 hooks to integrate custom Anti-Money Laundering (AML) and Counter-Financing of Terrorism (CFT) mechanisms alongside investor protection safeguards directly into liquidity pools.
  • Expanded Asset Deployment: Extending liquidity provisioning across digital assets, stablecoins, and real-world assets (RWAs).

Organizational Roles

The consortium divides strategic responsibilities across traditional financial compliance, protocol engineering, and security research:

  • SMBC Nikko (Co-lead): Directs regulatory dialogue with authorities such as Japan’s Financial Services Agency (JFSA) while leading compliance, risk modeling, and portfolio management strategies.
  • Nethermind (Co-lead): Oversees technical architecture, engineering delivery, AI strategy, smart contract security, and liquidity hook validation.
  • Uniswap Labs: Provides technical integration expertise and liquidity deployment strategies for the Uniswap Protocol.
  • Base: Supports deployment within the Ethereum Layer 2 ecosystem, focusing on technical feedback for agentic payment infrastructure such as the x402 open protocol.
  • Nyx Foundation: Advises on custom hook structures, advanced market-making strategies, and security optimization.

Project updates will be regularly shared with the Financial Services Agency of Japan (JFSA) as regulators continue evaluating appropriate legal frameworks for decentralized finance in the country.


SMBC Nikko Partners with Nethermind to Bridge TradFi and DeFi via Agentic AI
SMBC Nikko Securities has entered into a strategic collaboration with blockchain infrastructure firm Nethermind, aiming to prototype a secure, compliant gateway for Japanese investors to access Decentralized Finance (DeFi) markets, utilizing advanced “agentic AI” to manage trading and risk. The initiative marks a pivotal step for one of Japan’s

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